Cov ntsiav tshuaj hloov zuj zus los ntawm cov tshuaj, pib hauv xyoo 1840s. Los ntawm lub xyoo pua puv 19, nrog rau kev tshwm sim thiab kev txhim kho txuas ntxiv ntawm cov tshuab ntsiav tshuaj, cov ntsiav tshuaj ntau lawm thiab daim ntawv thov tsim sai heev. Nyob rau hauv xyoo tsis ntev los no, ntsiav tshuaj cov cuab yeej siv tshuab thiab tshuab kuj tau pom qhov kev nce qib tseem ceeb, xws li cov ntaub so ntswg granulation, ncaj qha compression ntawm tag nrho cov hmoov, semi- zaj duab xis txheej, excipients tshiab, txheej txheem tshiab, thiab cov kab ntau lawm.
Kev tshawb fawb thiab tsim cov tshuaj suav tshuaj (TCM) cov ntsiav tshuaj tsuas yog pib thaum xyoo 1950. Nrog rau kev tshawb fawb dav dav hauv TCM chemistry, pharmacology, formulation, thiab kev siv tshuaj kho mob, ntau yam thiab ntau ntawm cov ntsiav tshuaj TCM tau nce ntxiv, kev siv thev naus laus zis tau txhim kho, thiab cov ntsiav tshuaj zoo tau maj mam nce. Hais txog hom, TCM ntsiav tshuaj suav nrog tsis yog tsuas yog cov ntsiav tshuaj compressed thiab qab zib xwb- cov ntsiav tshuaj coated, tab sis kuj tseem muaj cov ntsiav tshuaj microcapsule, lozenges, ntsiav tshuaj sab nraud, thiab cov ntsiav tshuaj effervescent. Raws li cov txheej txheem ntawm cov ntsiav tshuaj ntau lawm, txheej txheem txheej txheem tsim nyog rau TCM cov ntsiav tshuaj ntau lawm tau maj mam tsim. Piv txwv li, kev paub dhau los tau sau tseg hauv kev npaj cov ntsiav tshuaj uas muaj cov roj ntsha roj thiab cov roj tsis hloov pauv, txhim kho cov ntsiav tshuaj hardness, disintegration, thiab cov ntsiav tshuaj txheej, ua rau kev txhim kho zoo tas li.
Tsis tas li ntawd, kev tshawb fawb txog kev sib cais thiab bioavailability ntawm cov tshuaj nyob rau hauv cov tshuaj suav tshuaj ntsiav tshuaj yog maj mam pib. Hauv cov ntsiab lus, cov ntsiav tshuaj tau dhau los ua ib qho ntawm cov ntawv siv ntau yam nrog ntau yam, ntim ntau lawm, kev siv dav tshaj plaws, siv yooj yim thiab khaws cia, thiab ruaj khov zoo. Cov ntsiav tshuaj suav nrog ntau dua ib -feem peb ntawm cov kev npaj suav nrog hauv cov tshuaj pharmacopoeias ntawm Tuam Tshoj thiab ntau lub tebchaws, qhia txog lawv cov ntawv thov dav.
